Dr Andrew Cridge

Research Fellow
Andrew Cridge3
  • Biochemistry Department
  • School of Biomedical Sciences
  • University of Otago
  • P.O. Box 56
  • 710 Cumberland St
  • Dunedin 9054 , New Zealand
  • Tel.: 64 3 479-4673
  • Fax: 64 3 479-7866
  • Email:andrew.cridge@otago.ac.nz

My research focuses on environmental physiology, specifically how insects adapt to changes in
their environment and coordinate that at a molecular level during embryonic development. Aligned to
this I am also interested in how epigenetics can control gene expression through regulating transcription
and translation in response to external environmental signals, especially during development. The aim of
my research is to develop an understanding of the cellular response to environmental cues and how that
affects normal development. I have an additional interest in global change biology and am involved in a
longitudinal study to assess the impact of land use on bacterial fauna by determining the loss of
biodiversity in bacterial species using metagenomics. I am also passionate about science communication
and teaching and have active research interests in these areas.

Research Interest

  • Evolution of insect development
  • Transcription and translation control in growth and differentiation
  • Genome structure organization and its role in gene expression
  • The impact of land use on bacterial biodiversity

Background

B.Sc. (Hons), Lincoln University (1994). Ph.D. Otago University (2005).

Post-Doctoral fellow University of Manchester (UK) (2006-2008) and Massey University, Albany (NZ) (2008-2012).

Awards

  • 2015, Health Sciences Research Translation Award, Runner-up

Selected Publications

Andrew A Cridge and Belinda J Cridge., Rural school outreach in New Zealand: DNA, PCR and forging a career in science., Biochemist 2015 vol. 37 (5) pp. 32-33.,

Book Chapter

Osborne, A., Duncan, E. J., Cridge, A. G. and Dearden, P. K. (2014) Epigenetic and the maternal germline. In Translational epigenetics: Evidence and debate. 27-41 Tollefsbol, T. O. Ed. Academic Press, London UK.

Poole, E. S., Major, L. L., Cridge, A. G. and Tate, W. P. (2004) The Mechanism of recoding in pro- and eukaryotes. In Protein Synthesis and Ribosome Structure: Translating the genome. 397-428 Nierhaus, K. H. and Wilson, D. N. Eds. Wiley-VCH, Weinheim, Germany

Refereed Journal Article - Science

Cridge, A. G., Dearden, P. K, and Brownfield L.R. (2016) Convergent occurrence of the developmental hourglass in plant and animal embryogenesis? Annals of Botany, published online, DOI:10.1093/aob/mcw024

The Bumblebee genome sequencing consortium (includes Cridge, A.G.) (2015) The genomes of two key bumblebee species with primitive eusocial organization. Genome Biology 16(1):76

Cahyani, I., Cridge, A.G., Engelke, D.R., Ganley, A.R.D., and O'Sullivan, J.M (2015) A sequence-specific interaction between the Saccharomyces cerevisiae rRNA gene repeats and a locus encoding an RNA polymerase I subunit affects ribosomal DNA stability Molecular and Cellular Biology 35(3):544-554

Cridge, A. G., Leask, P. L., Duncan, E. J. and Dearden, P. K. (2015) What Do Studies of Insect Polyphenisms Tell Us about Nutritionally-Triggered Epigenomic Changes and Their Consequences? Nutrients 7(3):1787-1797

Cridge, A.G., Visweswaraiah, J., Ramesh, R. and Sattlegger, E. (2014) Semi-quantitative Colony Immunoassay for determining and optimizing protein expression in Saccharomyces cerevisiae and Escherichia coli. Analytical Biochemistry 447(1):82-89

O’Sullivan, J. M., Pai, D. A., Cridge, A. G., Engelke, D and Ganley, A. R. D. (2013) The nucleolus: a raft adrift in the nuclear sea or the keystone in nuclear structure? Biomolecular Concepts 4(3):277-286

Ganegama-Arachchi, G. J., Cridge, A, G., Dias-Wanigasekera, B. M., Cruz, C. D., McIntyre, L., Liu R., Flint, S., H. and Mutukumira, A. N. (2013) Effectiveness of Listeria phages in the decontamination of Listeria monocytogenes adhered to clean stainless steel, stainless steel coated with fish protein and as a biofilm. Journal of Industrial Microbiology and Biotechnology 40(10):1105-1116

Cridge, A. G., Castelli, L. M., Smirnova, J. B., Selley, J. N., Rowe, W., Hubbard, S. J., McCarthy, J. E., Ashe, M. P., Grant, C. M., and Pavitt, G. D. (2010) Identifying eIF4E-binding protein translationally-controlled transcripts reveals links to mRNAs bound by specific PUF proteins. Nucleic Acids Research 38(22):8039-8050.

Smith, J. M., Cridge, A. G. and Dearden, P. K. (2010) Germ cell specific and ovary structure in the rotifer Brachionus plicatilis. EvoDevo 1(1):5

Cridge, A. G., Major, L. L., Mahagaonkar, A. A., Poole, E. S., Isaksson, L. A. and Tate, W. P. (2006) Comparison of characteristics and functions of translation termination signals between and within prokaryotic and eukaryotic organisms. Nucleic Acids Research 34(5):1959-1973

Refereed Journal Article - Education

Cridge B., J., and Cridge, A.G. (2015) Evaluating how universities engage school students with science: a model based on the analysis of the literature Australian Universities’ Review 57(1), 34-44

 Bray B., J. and Cridge, A.G. (2013) Can education programmes effect long-term behavioural change? International Journal of Innovative Interdisciplinary Research 2(2):27-33.