Professor Tony Merriman

TonyMerriman4
  • Biochemistry Department
  • School of Biomedical Sciences
  • University of Otago
  • P.O. Box 56
  • 710 Cumberland St
  • Dunedin 9054 , New Zealand
  • Tel.: 64 3 479-7846
  • Fax: 64 3 479-7866
  • Email:tony.merriman@otago.ac.nz

Research Interests:

Our research group takes a genetic approach to understanding the biology of human disease. Currently we have four primary research projects.

1. Gout - the genetic causes and how these genes interact with the environment.

2. Genetics of autoimmune disease (mainly rheumatoid arthritis)

3. A genetic relationship between rheumatoid arthritis and schizophrenia.

4. Copy number variable genes and disease.


Our group is involved in these networks and extended collaborations

1. CCRep, a charitable trust whose key objective is clinical research

2. MapNet, a New Zealand cross sector organisation of geneticists

3. Middlemore Maaori Gout Action Group

4. The New Zealand Rheumatology Research Network (Dr Nicola Dalbeth, A/Prof Peter Gow, Dr Andrew Harrison, Prof John Highton, A/Prof Peter JonesA/Prof Lisa Stamp)

5. Ngati Porou Hauora

6. Virtual Institute of Statistical Genetics, developing advanced methods for statistical genomic analysis


Our group also collaborates with:

1. Dr Mik Black on analysis of copy number variation in next-generation sequencing data

2. A/Prof Greg Jones on the genetics of abdominal aortic aneurysm

3. Dr Benedicte Lie on the genetics of rheumatoid arthritis

4. Dr Rebecca Roberts on the genetics of inflammatory bowel disease

5. Dr Sophia Steeron the genetics of rheumatoid arthritis

6. Prof Paul Wordsworth on the genetics of rheumatoid arthritis

 

Links with, and funding and support from these organisations are important to us:

1. Arthritis New Zealand

2. Genetics Otago

3. Health Research Council of New Zealand

4. New Zealand Rheumatology Association

 

PhD projects available in this laboratory

Awards

  • Tony Merriman
  • 2016, Elected as Fellow of the Royal Society of New Zealand
  • Marilyn Merriman
  • 2016, BMS Research Support – Focused Contribution Award
  • Tanya Flynn
  • 2014, Bob Grigor Award for the best presentation by a Registrar / Trainee
  • At the New Zealand Rheumatology Association with New Zealand Health Professionals in Rheumatology Annual Scientific Meeting 2014
  • Tony Merriman
  • 2014, OSMS Maori and Pasifika Research Award
  • Tony Merriman
  • 2013, Australian Rheumatology Association's Best Basic Science Paper for 2013 Award
  • Tony Merriman
  • 2013, OSMS Senior Researcher Award
  • "for sustained research excellence over a period of time, with particular emphasis on the last five years"

Selected Publications

Lisa K Stamp, Tony Merriman, Christopher Frampton, Mei Zhang, Mary Wallace, Jeffrey N Miner, and Nicola Dalbeth., Plasma oxypurinol as a measure of adherence in clinical trials., Annals of the Rheumatic Diseases 2017 p. annrheumdis-2016-210661., Link »

Tony Merriman and Robert Terkeltaub., PPARGC1B: insight into the expression of the gouty inflammation phenotype: PPARGC1B and gouty inflammation., Rheumatology (Oxford) 2016 p. kew453., Link »

Murray Cadzow, Tony R Merriman, James Boocock, Nicola Dalbeth, Lisa K Stamp, Michael A Black, Peter M Visscher, and Phillip L Wilcox., Lack of direct evidence for natural selection at the candidate thrifty gene locus, PPARGC1A., BMC Med Genet 2016 vol. 17 (1) p. 80., Link »

J S Antoun, W M Thomson, T R Merriman, and M Farella, Self-Reported Oral Behaviour Habits in Hyperdivergent and Normodivergent Facial Types., J Oral Rehabil 2016., Link »

M Pirro, M R Mannarino, V Bianconi, S De Vuono, A Sahebkar, F Bagaglia, L Franceschini, A M Scarponi, E Mannarino, and T Merriman., Uric acid and bone mineral density in postmenopausal osteoporotic women: the link lies within the fat., Osteoporos Int 2016., Link »

S McCormick, T Kader, C Porteous, G Jones, and N Dickerhof., Ribose-Cysteine Increases Glutathione-Based Antioxidant Status and Reduces Atherosclerosis in Apoe-Deficient Mice., Atherosclerosis 2016 vol. 252 pp. E97-E98., Link »

Pedro M Azevedo, Tony R Merriman, Ruth K Topless, Nigel J Wilson, Sue Crengle, and Diana R Lennon., Association study involving polymorphisms in IL-6, IL-1RA, and CTLA4 genes and rheumatic heart disease in New Zealand population of Māori and Pacific ancestry., Cytokine 2016 vol. 85 pp. 201-206., Link »

Sarah E Morton, Kirstie J M O'Hare, Jaimee L K Maha, Max P Nicolson, Liana Machado, Ruth Topless, Tony R Merriman, and Richard J Linscott., Testing the Validity of Taxonic Schizotypy Using Genetic and Environmental Risk Variables., Schizophr Bull 2016 p. sbw108., Link »

Philip C Robinson, Hyon K Choi, Ron Do, and Tony R Merriman., Insight into rheumatological cause and effect through the use of Mendelian randomization., Nat Rev Rheumatol 2016 vol. 12 (8) pp. 486-496., Link »

Elena López-Isac, Jose-Ezequiel Martín, Shervin Assassi, Carmen P Simeón, Patricia Carreira, Norberto Ortego-Centeno, Mayka Freire, Emma Beltrán, Javier Narváez, Juan J Alegre-Sancho, Spanish Scleroderma Group, Benjamín Fernández-Gutiérrez, Alejandro Balsa, Ana M Ortiz, Miguel A González-Gay, Lorenzo Beretta, Alessandro Santaniello, Chiara Bellocchi, Claudio Lunardi, Gianluca Moroncini, Armando Gabrielli, Torsten Witte, Nicolas Hunzelmann, Jörg H W Distler, Gabriella Riekemasten, Annete H van der Helm-van Mil, Jeska de Vries-Bouwstra, Cesar Magro-Checa, Alexandre E Voskuyl, Madelon C Vonk, Øyvind Molberg, Tony Merriman, Roger Hesselstrand, Annika Nordin, Leonid Padyukov, Ariane Herrick, Steve Eyre, Bobby P C Koeleman, Christopher P Denton, Carmen Fonseca, Timothy R D J Radstake, Jane Worthington, Maureen D Mayes, and Javier Martin., Cross-disease Meta-analysis of Genome-wide Association Studies for Systemic Sclerosis and Rheumatoid Arthritis Reveals IRF4 as a New Common Susceptibility Locus., Arthritis Rheumatol 2016., Link »

Nicola Dalbeth, Tony R Merriman, and Lisa K Stamp., Gout., Lancet 2016.,

Humaira Rasheed, Amanda J Phipps-Green, Ruth Topless, Malcolm D Smith, Catherine Hill, Susan Lester, Maureen Rischmueller, Matthijs Janssen, Timothy L Jansen, Leo A Joosten, Timothy R Radstake, Philip L Riches, Anne-Kathrin Tausche, Frédéric Lioté, Alexander So, Andre van Rij, Gregory T Jones, Sally P McCormick, Andrew A Harrison, Lisa K Stamp, Nicola Dalbeth, and Tony R Merriman., Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout., Rheumatology (Oxford) 2016 p. kew057., Link »

Sirisha Mitnala, Amanda Phipps-Green, Christopher Franklin, Anne Horne, Lisa K Stamp, Tony R Merriman, and Nicola Dalbeth., Clinical and genetic features of diuretic-associated gout: a case-control study., Rheumatology (Oxford) 2016 p. kew018., Link »

R L Roberts, M C Wallace, A J Phipps-Green, R Topless, J M Drake, P Tan, N Dalbeth, T R Merriman, and L K Stamp., ABCG2 loss-of-function polymorphism predicts poor response to allopurinol in patients with gout., Pharmacogenomics J 2016., Link »

Humaira Rasheed, Cushla Mckinney, Lisa K Stamp, Nicola Dalbeth, Ruth K Topless, Richard Day, Diluk Kannangara, Kenneth Williams, Malcolm Smith, Matthijs Janssen, Tim L Jansen, Leo A Joosten, Timothy R Radstake, Philip L Riches, Anne-Kathrin Tausche, Frédéric Lioté, Leo Lu, Eli A Stahl, Hyon K Choi, Alexander So, and Tony R Merriman., The Toll-Like Receptor 4 (TLR4) Variant rs2149356 and Risk of Gout in European and Polynesian Sample Sets., PLoS ONE 2016 vol. 11 (1) p. e0147939., Link »

Daniel F B Wright, Stephen B Duffull, Tony R Merriman, Nicola Dalbeth, Murray L Barclay, and Lisa K Stamp., Predicting allopurinol response in patients with gout., Brit J Clin Pharmaco 2015, Link »

Cushla Mckinney, Lisa K Stamp, Nicola Dalbeth, Ruth K Topless, Richard O Day, Diluk Rw Kannangara, Kenneth M Williams, Matthijs Janssen, Timothy L Jansen, Leo A Joosten, Timothy R Radstake, Philip L Riches, Anne-Kathrin Tausche, Frédéric Lioté, Alexander So, and Tony R Merriman., Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout., Arthritis Res Ther 2015 vol. 17 (1) p. 288., Link »

James Boocock, David Chagné, Tony R Merriman, and Michael A Black., The distribution and impact of common copy-number variation in the genome of the domesticated apple, Malus x domestic Borkh., BMC Genomics 2015 vol. 16 (1) p. 848., Link »

R K Topless, T J Flynn, M Cadzow, L K Stamp, N Dalbeth, M A Black, and T R Merriman., Association of SLC2A9 genotype with phenotypic variability of serum urate in pre-menopausal women., Front Genet 2015 vol. 6 (OCT)., Link »

Anna L Gosling, Hallie R Buckley, Elizabeth Matisoo-Smith, and Tony R Merriman., Pacific Populations, Metabolic Disease and 'Just-So Stories': A Critique of the 'Thrifty Genotype' Hypothesis in Oceania., Ann Hum Genet 2015, Link »

Tahzeeb Fatima, Sara Altaf, Amanda Phipps-Green, Ruth Topless, Tanya J Flynn, Lisa K Stamp, Nicola Dalbeth, and Tony R Merriman., Association analysis of the beta-3 adrenergic receptor Trp64Arg (rs4994) polymorphism with urate and gout., Rheumatology International 2015, Link »

Nicola Dalbeth, Amanda Phipps-Green, Meaghan E House, Gregory D Gamble, Anne Horne, Lisa K Stamp, and Tony R Merriman., Body mass index modulates the relationship of sugar-sweetened beverage intake with serum urate concentrations and gout., Arthritis Res Ther 2015 vol. 17 (1) p. 263., Link »

Tanya J Flynn, Murray Cadzow, Nicola Dalbeth, Peter B Jones, Lisa K Stamp, Jennie Harré Hindmarsh, Alwyn S Todd, Robert J Walker, Ruth Topless, and Tony R Merriman., Positive association of tomato consumption with serum urate: support for tomato consumption as an anecdotal trigger of gout flares., BMC Musculoskelet Disord 2015 vol. 16 (1) p. 196., Link »

Laura B E Kienhorst, Ellen van Lochem, Wietske Kievit, Nicola Dalbeth, Marilyn E Merriman, Amanda Phipps-Green, Arnoud Loof, Waander van Heerde, Sita Vermeulen, Lisa K Stamp, Elly van Koolwijk, Jacqueline de Graaf, Dirk Holzinger, Johannes Roth, Hein J E M Janssens, Tony R Merriman, Jasper C A Broen, Matthijs Janssen, and Timothy R D J Radstake., Gout is a chronic inflammatory disease where high levels of interleukin 8 (CXCL8), MRP8/14 and an altered proteome associate with diabetes and cardiovascular disease., Arthritis Rheumatol 2015, Link »

Richard J Johnson, Tony Merriman, and Miguel A Lanaspa., Causal or Noncausal Relationship of Uric Acid With Diabetes., Diabetes 2015 vol. 64 (8) pp. 2720-2722., Link »

R L Roberts, M C Wallace, A Harrison, N Dalbeth, T R Merriman, and L K Stamp., A human leukocyte antigen locus haplotype confers risk for allopurinol-related adverse effects in Caucasian patients with gout., Pharmacogenet Genom 2015 vol. 25 (8) pp. 412-415., Link »

Philip C Robinson and Tony R Merriman, Does midlife obesity really lower dementia risk?, Lancet Diabetes Endocrinol 2015 vol. 3 (7) p. 501., Link »

Nicola Dalbeth, Ruth Topless, Tanya Flynn, Murray Cadzow, Mark J Bolland, and Tony R Merriman., Mendelian randomization analysis to examine for a causal effect of urate on bone mineral density., J Bone Miner Res 2015 vol. 30 (6) pp. 985-991., Link »

R Murphy, S Thornley, J De Zoysa, L K Stamp, N Dalbeth, and T R Merriman., Sugar sweetened beverage consumption among adults with gout or type 2 diabetes., PLoS ONE 2015 vol. 10 (5), Link »

L K Stamp, T R Merriman, M L Barclay, J A Singh, R L Roberts, D F B Wright, and N Dalbeth., Impaired response or insufficient dosage?-Examining the potential causes of "inadequate response" to allopurinol in the treatment of gout., Semin Arthritis Rheum 2015 vol. 44 (2) pp. 170-174., Link »

Tony R Merriman., An update on the genetic architecture of hyperuricemia and gout., Arthritis Res Ther 2015 vol. 17 (1) p. 98, Link »

Jennifer E Huffman, Eva Albrecht, Alexander Teumer, Massimo Mangino, Karen Kapur, Toby Johnson, Zoltán Kutalik, Nicola Pirastu, Giorgio Pistis, Lorna M Lopez, Toomas Haller, Perttu Salo, Anuj Goel, Man Li, Toshiko Tanaka, Abbas Dehghan, Daniela Ruggiero, Giovanni Malerba, Albert V Smith, Ilja M Nolte, Laura Portas, Amanda Phipps-Green, Lora Boteva, Pau Navarro, Asa Johansson, Andrew A Hicks, Ozren Polasek, Tõnu Esko, John F Peden, Sarah E Harris, Federico Murgia, Sarah H Wild, Albert Tenesa, Adrienne Tin, Evelin Mihailov, Anne Grotevendt, Gauti K Gislason, Josef Coresh, Pio D'Adamo, Sheila Ulivi, Peter Vollenweider, Gerard Waeber, Susan Campbell, Ivana Kolcic, Krista Fisher, Margus Viigimaa, Jeffrey E Metter, Corrado Masciullo, Elisabetta Trabetti, Cristina Bombieri, Rossella Sorice, Angela Döring, Eva Reischl, Konstantin Strauch, Albert Hofman, Andre G Uitterlinden, Melanie Waldenberger, H-Erich Wichmann, Gail Davies, Alan J Gow, Nicola Dalbeth, Lisa Stamp, Johannes H Smit, Mirna Kirin, Ramaiah Nagaraja, Matthias Nauck, Claudia Schurmann, Kathrin Budde, Susan M Farrington, Evropi Theodoratou, Antti Jula, Veikko Salomaa, Cinzia Sala, Christian Hengstenberg, Michel Burnier, Reedik Mägi, Norman Klopp, Stefan Kloiber, Sabine Schipf, Samuli Ripatti, Stefano Cabras, Nicole Soranzo, Georg Homuth, Teresa Nutile, Patricia B Munroe, Nicholas Hastie, Harry Campbell, Igor Rudan, Claudia Cabrera, Chris Haley, Oscar H Franco, Tony R Merriman, Vilmundur Gudnason, Mario Pirastu, Brenda W Penninx, Harold Snieder, Andres Metspalu, Marina Ciullo, Peter P Pramstaller, Cornelia M van Duijn, Luigi Ferrucci, Giovanni Gambaro, Ian J Deary, Malcolm G Dunlop, James F Wilson, Paolo Gasparini, Ulf Gyllensten, Tim D Spector, Alan F Wright, Caroline Hayward, Hugh Watkins, Markus Perola, Murielle Bochud, W H Linda Kao, Mark Caulfield, Daniela Toniolo, Henry Völzke, Christian Gieger, Anna Köttgen, and Veronique Vitart., Modulation of genetic associations with serum urate levels by body-mass-index in humans., PLoS ONE 2015 vol. 10 (3) p. e0119752., Link »

F Perez-Ruiz, M A Aniel-Quiroga, A M Herrero-Beites, S P Chinchilla, G G Erauskin, and T Merriman., Renal clearance of uric acid is linked to insulin resistance and lower excretion of sodium in gout patients., Rheumatology International 13 March 2015, 6p, Link »

L Bossini-Castillo, C de Kovel, H Kallberg, R van't Slot, A Italiaander, M Coenen, P P Tak, M D Posthumus, C Wijmenga, T Huizinga, A H M van der Helm-van Mil, G Stoeken-Rijsbergen, L Rodriguez-Rodriguez, A Balsa, I González-álvaro, M A Gonzalez-Gay, C Gómez-Vaquero, B Franke, S Vermeulen, I E van der Horst-Bruinsma, B A C Dijkmans, G J Wolbink, R A Ophoff, M T Maehlen, P van Riel, M Merriman, L Klareskog, B A Lie, T Merriman, J B A Crusius, E Brouwer, J Martín, N de Vries, R Toes, L Padyukov, and B P C Koeleman, A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides, Annals of the Rheumatic Diseases 2015, (74) 3, Link »

J D Doecke, L A Simms, Z Z Zhao, R L Roberts, E V Fowler, A Croft, A Lin, N Huang, D C Whiteman, T H J Florin, M L Barclay, T R Merriman, R B Gearry, G W Montgomery, and G L Radford-Smith., Smoking behaviour modifies IL23r-associated disease risk in patients with Crohn's disease., Journal of Gastroenterology and Hepatology (Australia) 2015 vol. 30 (2) pp. 299-307., Link »

Humaira Rasheed, Kim Hughes, Tanya J Flynn, and Tony R Merriman, Mendelian Randomization Provides No Evidence for a Causal Role of Serum Urate in Increasing Serum Triglyceride Levels., Circulation Cardiovascular genetics 2014, Link »

A J Phipps-Green, M E Merriman, R Topless, S Altaf, G W Montgomery, C Franklin, G T Jones, A M van Rij, D White, L K Stamp, N Dalbeth, and T R Merriman, Twenty-eight loci that influence serum urate levels: analysis of association with gout., Annals of the Rheumatic Diseases 2014, Link »

Cadzow, M., Boocock, J., Nguyen, H. T., Wilcox, P., Merriman, T. R., & Black, M. A., A bioinformatics workflow for detecting signatures of selection in genomic data, Frontiers in Genetics (2014) 5, 293, Link »

Andrea L Vincent, Charlotte A Jordan, Murray J Cadzow, Tony R Merriman, and Charles N J McGhee, Mutations in the zinc finger protein gene, ZNF469, contribute to the pathogenesis of keratoconus., Investigative ophthalmology & visual science 2014, Link »

Nguyen, H. T., Merriman, T. R., & Black, M. A., The CNVrd2 package: Measurement of copy number at complex loci using high-throughput sequencing data. , Frontiers in Genetics (2014) 5(AUG), 248, Link »

Anna L Gosling, Elizabeth Matisoo-Smith, and Tony R Merriman, Hyperuricaemia in the Pacific: why the elevated serum urate levels?, Rheumatology International 2014 vol. 34 (6) pp. 743-757, Link »

Wen-Hua Wei, Yunfei Guo, Alida S D Kindt, Tony R Merriman, Colin A Semple, Kai Wang, and Chris S Haley, Abundant local interactions in the 4p16.1 region suggest functional mechanisms underlying SLC2A9 associations with human serum uric acid., Human Molecular Genetics 2014, Link »

Lisa K Stamp, Tony R Merriman, Murray L Barclay, Jasvinder A Singh, Rebecca L Roberts, Daniel F B Wright, and Nicola Dalbeth, Impaired response or insufficient dosage?-Examining the potential causes of "inadequate response" to allopurinol in the treatment of gout., Seminars in arthritis and rheumatism 2014, Link »

A L Gosling, E Matisoo-smith, and T R Merriman, Gout in mori: Modern affliction or ancestral trait?, Rheumatology (United Kingdom) 2014 vol. 53 (5) pp. 773-774, Link »

T R Merriman, H K Choi, and N Dalbeth, The Genetic Basis of Gout, Rheumatic Disease Clinics of North America 2014 vol. 40 (2) pp. 279-290, Link »

Rebecca L Roberts, Mary C Wallace, Daniel F B Wright, Murray Cadzow, Nicola Dalbeth, Peter B Jones, Lisa K Stamp, Andrew A Harrison, Michael A Black, and Tony R Merriman, Frequency of CYP2C9 polymorphisms in polynesian people and potential relevance to management of gout with benzbromarone., Joint, bone, spine : revue du rhumatisme 2014 vol. 81 (2) pp. 160-163, Link »

Anna L Mitchell, Katie D R Macarthur, Earn H Gan, Lucy E Baggott, Anette S B Wolff, Beate Skinningsrud, Hazel Platt, Andrea Short, Anna Lobell, Olle Kämpe, Sophie Bensing, Corrado Betterle, Anna Kasperlik-Zaluska, Magdalena Zurawek, Marta Fichna, Ingrid Kockum, Gabriel Nordling Eriksson, Olov Ekwall, Jeanette Wahlberg, Per Dahlqvist, Anna-Lena Hulting, Marissa Penna-Martinez, Gesine Meyer, Heinrich Kahles, Klaus Badenhoop, Stephanie Hahner, Marcus Quinkler, Alberto Falorni, Amanda Phipps-Green, Tony R Merriman, William Ollier, Heather J Cordell, Dag Undlien, Barbara Czarnocka, Eystein Husebye, and Simon H S Pearce, Association of Autoimmune Addison's Disease with Alleles of STAT4 and GATA3 in European Cohorts., PLoS ONE 2014, Link »

Kim Hughes, Tanya Flynn, Janak de Zoysa, Nicola Dalbeth, and Tony R Merriman, Mendelian randomization analysis associates increased serum urate, due to genetic variation in uric acid transporters, with improved renal function., Kidney international 2013 vol. 62 pp. 543-550, Link »

N Dalbeth, M E House, G D Gamble, B Pool, A Horne, L Purvis, A Stewart, M Merriman, M Cadzow, A Phipps-Green, and T R Merriman, Influence of the ABCG2 gout risk 141 K allele on urate metabolism during a fructose challenge, Arthritis research & therapy 2014 vol. 16 (1), Link »

Tanya J Flynn, Amanda Phipps-Green, Jade E Hollis-Moffatt, Marilyn E Merriman, Ruth Topless, Grant Montgomery, Brett Chapman, Lisa K Stamp, Nicola Dalbeth, Tony R Merriman, Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case-control sample sets reveals multiple ancestral-specific effects, Arthritis research & therapy Volume 15, Issue 6, Page R220, Link »

H Rasheed, A Phipps-Green, R Topless, J E Hollis-Moffatt, J H Hindmarsh, C Franklin, N Dalbeth, P B Jones, D H N White, L K Stamp, and T R Merriman, Association of the lipoprotein receptor-related protein 2 gene with gout and non-additive interaction with alcohol consumption, Arthritis Research and Therapy Volume 15, Issue 6, Link »

J D Falvey, R W Bentley, T R Merriman, M B Hampton, M L Barclay, R B Gearry, and R L Roberts, Macrophage migration inhibitory factor gene polymorphisms in inflammatory bowel disease: An association study in New Zealand Caucasians and meta-analysis, World Journal of Gastroenterology 2013 vol. 19 (39) pp. 6656-6664, Link »

Merriman, Tony R, and Flynn, Tanya J, Molecular Genetics of Hyperuricaemia and Gout. , In: eLS. John Wiley & Sons Ltd, Chichester, Link »

Anna L Gosling, Elizabeth Matisoo-Smith, and Tony R Merriman, Gout in Maori, Rheumatology (Oxford, England) 2013, Link »

R L Roberts, M C Wallace, D F B Wright, M Cadzow, N Dalbeth, P B Jones, L K Stamp, A A Harrison, M A Black, and T R Merriman, Frequency of CYP2C9 polymorphisms in polynesian people and potential relevance to management of gout with benzbromarone, Joint Bone Spine 2013, Link »

J H Ngu, M C Wallace, T R Merriman, R B Gearry, C A M Stedman, and R L Roberts, Association of the HLA locus and TNF with type I autoimmune hepatitis susceptibility in New Zealand Caucasians, SpringerPlus 2013 vol. 2 (1) pp. 1-8, Link »

G T Jones, M J Bown, S Gretarsdottir, S P R Romaine, A Helgadottir, G Yu, G Tromp, P E Norman, C Jin, A F Baas, J D Blankensteijn, I J Kullo, L Victoria Phillips, M J A Williams, R Topless, T R Merriman, T M Vasudevan, D R Lewis, R D Blair, A A Hill, R D Sayers, J T Powell, P Deloukas, G Thorleifsson, S E Matthiasson, U Thorsteinsdottir, J Golledge, R A Ariëns, A Johnson, S Sohrabi, D Julian Scott, D J Carey, R Erdman, J R Elmore, H Kuivaniemi, N J Samani, K Stefansson, and A M van Rij, A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm, Human Molecular Genetics 2013 vol. 22 (14) pp. 2941-2947, Link »

H T Nguyen, T R Merriman, and M A Black, CNVrd, a Read-Depth Algorithm for Assigning Copy-Number at the FCGR Locus: Population-Specific Tagging of Copy Number Variation at FCGR3B, PLoS ONE 2013 vol. 8 (4), Link »

D F B Wright, L K Stamp, T R Merriman, M L Barclay, S B Duffull, and N H G Holford, The population pharmacokinetics of allopurinol and oxypurinol in patients with gout, European Journal of Clinical Pharmacology 2013 pp. 1-11, Link »

N Dalbeth, M E House, G D Gamble, A Horne, B Pool, L Purvis, A Stewart, M Merriman, M Cadzow, A Phipps-Green, and T R Merriman, Population-specific influence of SLC2A9 genotype on the acute hyperuricaemic response to a fructose load, Annals of the Rheumatic Diseases 2013, Link »

Philip C Robinson, Tony R Merriman, Peter Herbison, and John Highton, Hospital admissions associated with gout and their co-morbidities in New Zealand and England 1999-2009., Rheumatology (Oxford, England) , Link »

R Debono, R Topless, D Markie, M A Black, and T R Merriman, Analysis of the DISC1 translocation partner (11q14.3) in genetic risk of schizophrenia, Genes, Brain and Behavior 2012 vol. 11 (7) pp. 859-863, Link »

M Wilsher, L Voight, D Milne, M Teh, N Good, J Kolbe, M Williams, K Pui, T Merriman, K Sidhu, and N Dalbeth, Prevalence of airway and parenchymal abnormalities in newly diagnosed rheumatoid arthritis, Respiratory Medicine Volume 106, Issue 10, October 2012, Pages 1441–1446, Link »

Angela Hsu, Nicola Dalbeth, Peter Gow, Andrew Harrison, John Highton, Peter B Jones, Lisa K Stamp, and Tony R Merriman, No evidence for association of Chr 9p21 variant rs1333049 with gout in New Zealand case-control sample sets., Rheumatology (Oxford, England) 2012 vol. 51 (6) pp. 1129-1130, Link »

C Mckinney, J C A Broen, M C Vonk, L Beretta, R Hesselstrand, N Hunzelmann, G Riemekasten, R Scorza, C P Simeon, V Fonollosa, P E Carreira, N Ortego-Centeno, M A Gonzalez-Gay, P Airo, M Coenen, J Martín, T R D J Radstake, and T R Merriman, Evidence that deletion at FCGR3B is a risk factor for systemic sclerosis., Genes and Immunity 13, 458-460, Link »

Jade E Hollis-Moffatt, Amanda J Phipps-Green, Brett Chapman, Gregory T Jones, Andre van Rij, Peter J Gow, Andrew A Harrison, John Highton, Peter B Jones, Grant W Montgomery, Lisa K Stamp, Nicola Dalbeth, and Tony R Merriman, The renal urate transporter SLC17A1 locus: confirmation of association with gout., Arthritis research & therapy 2012 vol. 14 (2) p. R92, Link »

PC Robinson, WJ Taylor, and TR Merriman, A Systematic Review of the Prevalence of Gout and Hyperuricemia in Australia., Internal medicine journal Volume 42, Issue 9, pages 997–1007, September 2012, Link »

T.W. Eglinton, R. Roberts, J Pearson, M. Barclay, T R Merriman, F.A. Frizelle, and R B Gearry, Clinical and genetic risk factors for perianal Crohn's disease in a population-based cohort, American Journal of Gastroenterology 2012 vol. 107 (4) pp. 589-596, Link »

Cushla Mckinney and Tony R Merriman, Meta-analysis confirms a role for deletion in FCGR3B in autoimmune phenotypes., Human Molecular Genetics (2012), Link »

M Chen-Xu, R Topless, C Mckinney, M E Merriman, A Phipps-Green, N Dalbeth, P J Gow, A A Harrison, J Highton, P B Jones, M Nissen, M D Smith, A Van Rij, G T Jones, L Rodriguez-Rodriguez, B Fernandez-Gutierrez, M Teruel, A Balsa, D Pascual-Salcedo, A M Ortiz, M A Gonzalez-Gay, S Steer, M Maehlen, B Lie, B P Wordsworth, L K Stamp, J Martín, and T R Merriman, Replication of association of the interleukin 23 receptor rs1343151 variant with rheumatoid arthritis in Caucasian sample sets, Annals of the Rheumatic Diseases 2012 vol. 71 (1) pp. 155-157, Link »