More information is available on our lab website.
B.Sc., The Evergreen State College, USA (2002). Ph.D., Emory University, USA (2007). FRST Postdoctoral Fellow, Massey University (2008-2012).
Enquires about projects from prospective students are welcome and should be sent to firstname.lastname@example.org. Please include a CV and a decription of your research interests. Information on scholarships for postgraduate students can be found at the University of Otago's website at http://www.otago.ac.nz/study/scholarships/
Kopke, M., Patrick, W.M., Maddock, D.J. and Gerth, M.L. (2017) Enzyme-Altered Metabolite Activity. US patent No: US 9,550,979 B2. Granted 24 January, 2017.
Carl H Mesarich, Jonathan Rees-George, Paul P Gardner, Fatemeh Ashari Ghomi, Monica L Gerth, Mark T Andersen, Erik H A Rikkerink, Peter C. Fineran, and Matthew D Templeton., Transposon insertion libraries for the characterization of mutants from the kiwifruit pathogen Pseudomonas syringae pv. actinidiae., PLoS ONE 2017 vol. 12 (3) p. e0172790., Link »
Brewster, J.L., McKellar, J.L.O., Finn, T.J., Newman, J., Peat, T.S. and Gerth, M.L. (2016) Structural basis for ligand recognition by a Cache chemosensory domain that mediates carboxylate sensing in Pseudomonas syringae. Scientific Reports, doi:10.1038/srep35198.
Maddock, D.J., Patrick, W.M. and Gerth, M.L. (2015) Substitutions at the cofactor binding sites of a clostridial alcohol dehydrogenase lead to unexpected changes in substrate specificity. Protein Engineering, Design, and Selection, 28: 251-258.
McKellar, J.L., Minnell, J.J. and Gerth, M.L. (2015) A high-throughput screen for ligand binding reveals the specificities of three amino acid chemoreceptors from Pseudomonas syringae pv. actinidiae. Molecular Microbiology, 96:694-707.
Kopke, M., Gerth, M.L., Maddock, D.J., Mueller, A.P., Liew, F.M., Simpson, S.D. and Patrick, W.M. (2014) Reconstruction of an acetogenic 2,3-butanediol pathway involving a novel NADPH-dependent primary-secondary alcohol dehydrogenase. Applied and Environmental Microbiology, 80: 3394-3403.
Patrick, W.M. and Gerth, M.L. (2014) ITCHY: Incremental Truncation for the Creation of Hybrid Enzymes. Methods in Molecular Biology, Directed Enzyme Evolution, 1179:225-244.
Wilson, R.H., Morton, S.K., Deiderick, H., Gerth, M.L., Paul, H.A., Gerber, I., Patel, A., Ellington, A.D., Hunicke-Smith, S.P. and Patrick, W.M. (2013). Engineered DNA ligases with improved activities in vitro. Protein Engineering, Design and Selection, 26, 471-478.
Gerth, M.L., Ferla, M.P. and Rainey, P.B. (2012) The origin and ecological significance of multiple branches for histidine utilization in Pseudomonas aeruginosa PAO1. Environmental Microbiology, 14: 1929-1940.
Gerth, M.L., Lutz, S. (2007) Non-homologous recombination of deoxyribonucleoside kinases from human and Drosophila melanogaster yields human-like enzymes with novel activities. Journal of Molecular Biology, 370: 742-751.
Gerth, M.L., Patrick, W.M., Lutz, S. (2004) A second-generation system for unbiased reading frame selection. Protein Engineering, Design and Selection, 17: 595-602.