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Harold S Bernhardt and Wayne M Patrick, Journal of molecular evolution, 2014 vol. 78 (6) pp. 307-309
Ideas about the origin and evolution of the genetic code have come from many quarters, including theoretical and experimental biology, physics and even mathematics. One of the more interesting recent contributions to the debate is that of Maxim Makukov, a cosmologist and astrophysicist, who has proposed that the genetic code contains an encrypted message - possibly placed there by our extraterrestrial creators - and the message is...37! Somewhat more conservatively, we have previously proposed that the original genetic code coded only for the amino acid glycine, and in the current paper we suggest that the next amino acids encoded were similarly small and hydrophilic, resulting in the synthesis of water-soluble peptides.